Enhanced nigrostriatal neuron-specific, long-term expression by using neural-specific promoters in combination with targeted gene transfer by modified helper virus-free HSV-1 vector particles

BACKGROUND: Direct gene transfer into neurons has potential for developing gene therapy treatments for specific neurological conditions, and for elucidating neuronal physiology. Due to the complex cellular composition of specific brain areas, neuronal type-specific recombinant gene expression is req...

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Detalhes bibliográficos
Main Authors: Cao, Haiyan, Zhang, Guo-rong, Wang, Xiaodan, Kong, Lingxin, Geller, Alfred I
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330056/
https://ncbi.nlm.nih.gov/pubmed/18402684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-9-37
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