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Overexpression of either lysine-specific demethylase-1 or CLOCK, but not Co-Rest, improves long- term expression from a modified neurofilament promoter, in a helper virus-free HSV-1 vector system
Long-term expression from helper virus-free Herpes Simplex Virus (HSV-1) vectors is required for many specific neural gene therapies and studies on neuronal physiology. We previously developed a promoter that supports long-term, neuron-specific expression by fusing the chicken ß-globin insulator (IN...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3287058/ https://ncbi.nlm.nih.gov/pubmed/22208646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.12.011 |
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