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Reduced NHE3-mediated Na(+) absorption increases survival and decreases the incidence of intestinal obstructions in cystic fibrosis mice
In cystic fibrosis, impaired secretion resulting from loss of activity of the cystic fibrosis transmembrane conductance regulator (CFTR) causes dehydration of intestinal contents and life-threatening obstructions. Conversely, impaired absorption resulting from loss of the NHE3 Na(+)/H(+) exchanger c...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Physiological Society
2009
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670667/ https://ncbi.nlm.nih.gov/pubmed/19164484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90520.2008 |
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