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Reduced NHE3-mediated Na(+) absorption increases survival and decreases the incidence of intestinal obstructions in cystic fibrosis mice
In cystic fibrosis, impaired secretion resulting from loss of activity of the cystic fibrosis transmembrane conductance regulator (CFTR) causes dehydration of intestinal contents and life-threatening obstructions. Conversely, impaired absorption resulting from loss of the NHE3 Na(+)/H(+) exchanger c...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670667/ https://ncbi.nlm.nih.gov/pubmed/19164484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90520.2008 |
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