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AE2 Cl(−)/HCO(3)(−) exchanger is required for normal cAMP-stimulated anion secretion in murine proximal colon
Anion secretion by colonic epithelium is dependent on apical CFTR-mediated anion conductance and basolateral ion transport. In many tissues, the NKCC1 Na(+)-K(+)-2Cl(−) cotransporter mediates basolateral Cl(−) uptake. However, additional evidence suggests that the AE2 Cl(−)/HCO(3)(−) exchanger, when...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853300/ https://ncbi.nlm.nih.gov/pubmed/20110461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00178.2009 |
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