NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice

NHE3(−/−) mice display a profound defect in proximal tubule bicarbonate reabsorption but are only mildly acidotic owing to reduced glomerular filtration rate and enhanced H(+) secretion in distal nephron segments. In vivo microperfusion of rat distal tubules suggests that a significant fraction of b...

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Detalhes bibliográficos
Main Authors: Bailey, Matthew A, Giebisch, Gerhard, Abbiati, Thecla, Aronson, Peter S, Gawenis, Lara R, Shull, Gary E, Wang, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665379/
https://ncbi.nlm.nih.gov/pubmed/15604231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.074716
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