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Phospholemman regulates cardiac Na(+)/Ca(2+) exchanger by interacting with the exchanger's proximal linker domain
Phospholemman (PLM) belongs to the FXYD family of small ion transport regulators. When phosphorylated at Ser(68), PLM inhibits cardiac Na(+)/Ca(2+) exchanger (NCX1). We previously demonstrated that the cytoplasmic tail of PLM interacts with the proximal intracellular loop (residues 218–358), but not...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Physiological Society
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670646/ https://ncbi.nlm.nih.gov/pubmed/19158404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00196.2008 |
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