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Effects of SOD2 Silencing on Androgen Receptor Function and Gene Regulation: Implications for Castration-Resistant Prostate Cancer

PURPOSE: Advanced prostate cancer is first treated with androgen deprivation therapy. However, tumors become resistant to and grow despite castrate levels of testosterone. Growth and proliferation of castration-resistant prostate cancer (CRPC) is mediated by gain-of-function changes in the androgen...

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Bibliografski detalji
Glavni autori: Sharifi, Nima, Hurt, Elaine M., Thomas, Suneetha B., Farrar, William L.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670581/
https://ncbi.nlm.nih.gov/pubmed/18829485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0591
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