NASP implication in the androgen receptor associated with castration resistance in prostate cancer

Abstract Uncovering the mechanisms underlying tumor malignancy is extremely important for cancer treatment and management. In this study, using a pairwise cell model, LNCaP and its castration-resistant derivative C42B, we analyze the function of enhanced NASP protein in castration resistance. The da...

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Principais autores:	Yun Feng, Jin Sun, Xuan Kang, Yining Wang, Kai Liu, Wenfei Wang, Chen Wang, Yabin Li, Qian Zhao, Kaile Li, Fang-Lin Sun, Jianfeng Chang
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-07-01
Series:	Cell Communication and Signaling
Assuntos:	NASP Androgen receptor Prostate cancer EMT Histone turnover Epigenetic landscape
Acceso en liña:	https://doi.org/10.1186/s12964-025-02339-0
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