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Differential role of NF-κB in selection and survival of CD4 and CD8 thymocytes

Inhibition of NF-κB activity leads to a reduction in numbers of CD8(+) single positive (SP) thymocytes suggesting a selective role for NF-κB in these cells. To further explore the role of NF-κB in SP thymocytes we utilized transgenic models that allow either inhibition or activation of NF-κB. We now...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jimi, Eijiro, Voll, Reinhard E., Strickland, Ian, Long, Meixiao, Ghosh, Sankar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670481/
https://ncbi.nlm.nih.gov/pubmed/18957265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.08.010
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