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Repression of gene expression by unphosphorylated NF-κB p65 through epigenetic mechanisms

Cells from a “knock-in” mouse expressing a NF-κB p65 mutant bearing an alanine instead of serine at position 276 (S276A) display a significant reduction of NF-κB-dependent transcription, even though the mutant p65 forms appropriate complexes that translocate normally to the nucleus and bind to DNA....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dong, Jie, Jimi, Eijiro, Zhong, Haihong, Hayden, Matthew S., Ghosh, Sankar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335313/
https://ncbi.nlm.nih.gov/pubmed/18408078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1657408
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