Population pharmacokinetics of intravenous pantoprazole in paediatric intensive care patients

AIMS: To characterize the pharmacokinetics of intravenous pantoprazole in a paediatric intensive care population and to determine the influence of demographic factors, systemic inflammatory response syndrome (SIRS), hepatic dysfunction and concomitantly used CYP2C19 inducers and inhibitors on the dr...

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Bibliographic Details
Main Authors: Pettersen, Géraldine, Mouksassi, Mohamad-Samer, Théorêt, Yves, Labbé, Line, Faure, Christophe, Nguyen, Bao, Litalien, Catherine
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2009
Subjects:
Paediatric Clinical Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670379/
https://ncbi.nlm.nih.gov/pubmed/19173681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03328.x
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