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MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease

The MEP1A gene, located on human chromosome 6p (mouse chromosome 17) in a susceptibility region for inflammatory bowel disease (IBD), encodes the α-subunit of metalloproteinase meprin A, which is expressed in the intestinal epithelium. This study shows a genetic association of MEP1A with IBD in a co...

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Détails bibliographiques
Auteurs principaux: Banerjee, S, Oneda, B, Yap, LM, Jewell, DP, Matters, GL, Fitzpatrick, LR, Seibold, F, Sterchi, EE, Ahmad, T, Lottaz, D, Bond, JS
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670347/
https://ncbi.nlm.nih.gov/pubmed/19262505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2009.3
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