Targeted Transgenic Expression of an Osteoclastic Transmembrane Protein-tyrosine Phosphatase in Cells of Osteoclastic Lineage Increases Bone Resorption and Bone Loss in Male Young Adult Mice

This study evaluated whether transgenic expression of PTP-oc (osteoclastic transmembrane protein-tyrosine phosphatase) in cells of the osteoclast lineage would affect bone resorption and bone density in young adult mice. Transgenic mice were generated with a transgenic construct using a tartrate-res...

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Detalhes bibliográficos
Main Authors: Sheng, Matilda H.-C., Amoui, Mehran, Stiffel, Virginia, Srivastava, Apurva K., Wergedal, Jon E., Lau, K.-H. William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670158/
https://ncbi.nlm.nih.gov/pubmed/19244239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808324200
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