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Blunted Akt/FOXO signalling and activation of genes controlling atrophy and fuel use in statin myopathy
Statins are used clinically for cholesterol reduction, but statin therapy is associated with myopathic changes through a poorly defined mechanism. We used an in vivo model of statin myopathy to determine whether statins up-regulate genes associated with proteasomal- and lysosomal-mediated proteolysi...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670035/ https://ncbi.nlm.nih.gov/pubmed/19001041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.164699 |
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