Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant

Cetuximab and panitumumab efficacy in metastatic colorectal cancer (mCRC) may be influenced by EGFR gene status and/or deregulation of its downstream signalling proteins detected in primary tumour. However, metastasis might have different molecular patterns with respect to primary tumour, possibly a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Molinari, F, Martin, V, Saletti, P, De Dosso, S, Spitale, A, Camponovo, A, Bordoni, A, Crippa, S, Mazzucchelli, L, Frattini, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2009
Gaiak:
Molecular Diagnostics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669991/
https://ncbi.nlm.nih.gov/pubmed/19293803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604848
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