Differing deregulation of EGFR and downstream proteins in primary colorectal cancer and related metastatic sites may be clinically relevant

Cetuximab and panitumumab efficacy in metastatic colorectal cancer (mCRC) may be influenced by EGFR gene status and/or deregulation of its downstream signalling proteins detected in primary tumour. However, metastasis might have different molecular patterns with respect to primary tumour, possibly a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Molinari, F, Martin, V, Saletti, P, De Dosso, S, Spitale, A, Camponovo, A, Bordoni, A, Crippa, S, Mazzucchelli, L, Frattini, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669991/
https://ncbi.nlm.nih.gov/pubmed/19293803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604848
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados