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Oestrogen modulates experimental autoimmune encephalomyelitis and interleukin-17 production via programmed death 1

The mechanism by which oestrogens suppress experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis, is only partially understood. We here demonstrate that treatment with 17β-oestradiol (E(2)) in C57BL/6 mice boosted the expression of programmed death 1 (PD-1), a negati...

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Détails bibliographiques
Auteurs principaux: Wang, Chunhe, Dehghani, Babak, Li, Yuexin, Kaler, Laurie J, Vandenbark, Arthur A, Offner, Halina
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669813/
https://ncbi.nlm.nih.gov/pubmed/19302141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.03051.x
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