Localized α4 Integrin Phosphorylation Directs Shear Stress-Induced Endothelial Cell Alignment

Vascular endothelial cells respond to laminar shear stress by aligning in the direction of flow, a process which may contribute to athero-protection. Here we report that localized α4 integrin phosphorylation is a mechanism for establishing the directionality of shear stress-induced alignment in micr...

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Autori principali: Goldfinger, Lawrence E., Tzima, Eleni, Stockton, Rebecca, Kiosses, William B., Kinbara, Kayoko, Tkachenko, Eugene, Gutierrez, Edgar, Groisman, Alex, Nguyen, Phu, Chien, Shu, Ginsberg1, Mark H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669779/
https://ncbi.nlm.nih.gov/pubmed/18583710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.176354
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