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Spatial restriction of α4 integrin phosphorylation regulates lamellipodial stability and α4β1-dependent cell migration

Întegrins coordinate spatial signaling events essential for cell polarity and directed migration. Such signals from α4 integrins regulate cell migration in development and in leukocyte trafficking. Here, we report that efficient α4-mediated migration requires spatial control of α4 phosphorylation by...

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Detalhes bibliográficos
Main Authors: Goldfinger, Lawrence E., Han, Jaewon, Kiosses, William B., Howe, Alan K., Ginsberg, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173787/
https://ncbi.nlm.nih.gov/pubmed/12913113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304031
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