A Small Molecule Inhibitor of α4 Integrin-Dependent Cell Migration

A small molecule inhibitor of α4 integrin-dependent cell migration was identified through a cell–based screen of small molecule libraries. Biochemical and cellular experiments suggest that this molecule functions by interacting with γ-parvin. This molecule should serve as a useful tool to study α4 i...

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Bibliografiske detaljer
Main Authors: Lee, Jongkook, Hong, Jiyong, Nam, Tae-Gyu, Peters, Eric C., Orth, Anthony P., Geierstanger, Bernhard H., Goldfinger, Lawrence E., Ginsberg, Mark H., Cho, Charles Y., Schultz, Peter G.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951142/
https://ncbi.nlm.nih.gov/pubmed/18329275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.02.067
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