Nalaganje...

The Cleavage Products of Amyloid-β Precursor Protein Are Sorted to Distinct Carrier Vesicles That Are Independently Transported within Neurites

The amyloid-β (Aβ) precursor protein (APP), a transmembrane protein that undergoes proteolytic cleavage into defined fragments, has been implicated in axonal transport. The proposed role of APP as a vesicle receptor for the microtubule motor kinesin-1 has relevance for the pathogenesis of Alzheimer&...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Muresan, Virgil, Varvel, Nicholas H., Lamb, Bruce T., Muresan, Zoia
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669751/
https://ncbi.nlm.nih.gov/pubmed/19295161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2558-08.2009
Oznake: Označite
Brez oznak, prvi označite!