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mGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats

Addiction to methamphetamine is a significant public health problem, and there are currently no pharmacological agents that are approved for the treatment of addiction to this powerful psychostimulant. Chronic methamphetamine use leads to cognitive dysfunction as well as numerous psychiatric, neurol...

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Détails bibliographiques
Auteurs principaux: Gass, Justin T., Osborne, Megan P.H., Watson, Noreen L., Brown, Jordan L., Olive, M. Foster
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669746/
https://ncbi.nlm.nih.gov/pubmed/18800068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2008.140
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