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mGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats

Addiction to methamphetamine is a significant public health problem, and there are currently no pharmacological agents that are approved for the treatment of addiction to this powerful psychostimulant. Chronic methamphetamine use leads to cognitive dysfunction as well as numerous psychiatric, neurol...

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Autors principals: Gass, Justin T., Osborne, Megan P.H., Watson, Noreen L., Brown, Jordan L., Olive, M. Foster
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669746/
https://ncbi.nlm.nih.gov/pubmed/18800068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2008.140
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