CpG-oligodeoxynucleotides stimulate immunoglobulin A secretion in intestinal mucosal B cells

Bacterial DNA motifs (such as CpG-oligodeoxynucleotides: CpG-ODN) induce innate immune responses via binding to Toll-like-receptor-9 (TLR-9). In murine intestinal mucosa treatment with CpG-ODN worsens chronic intestinal inflammation, whereas it prevents or ameliorates colitis when given in a prophyl...

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Bibliographic Details
Main Authors: Blaas, S H, Stieber-Gunckel, M, Falk, W, Obermeier, F, Rogler, G
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2009
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669530/
https://ncbi.nlm.nih.gov/pubmed/19220839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03855.x
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