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Balance of Irgm protein activities determines IFN-γ-induced host defense
The immunity-related GTPases (IRG), also known as p47 GTPases, are a family of proteins that are tightly regulated by IFNs at the transcriptional level and serve as key mediators of IFN-regulated resistance to intracellular bacteria and protozoa. Among the IRG proteins, loss of Irgm1 has the most pr...
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| Huvudupphovsmän: | , , , , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Society for Leukocyte Biology
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669409/ https://ncbi.nlm.nih.gov/pubmed/19176402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1008599 |
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