Unconventional ligand activation of herpesvirus entry mediator signals cell survival

The herpesvirus entry mediator (HVEM; TNFRSF14) activates NF-κB through the canonical TNF-related cytokine LIGHT, serving as a costimulatory pathway during activation of T cells. HVEM also functions as a ligand for the Ig superfamily members B and T lymphocyte attenuator (BTLA) and CD160, both of wh...

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Main Authors: Cheung, Timothy C., Steinberg, Marcos W., Oborne, Lisa M., Macauley, Matthew G., Fukuyama, Satoshi, Sanjo, Hideki, D'Souza, Claire, Norris, Paula S., Pfeffer, Klaus, Murphy, Kenneth M., Kronenberg, Mitchell, Spear, Patricia G., Ware, Carl F.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2009
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669392/
https://ncbi.nlm.nih.gov/pubmed/19332782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902115106
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