T Cell Intrinsic Heterodimeric Complexes between HVEM and BTLA Determine Receptivity to the Surrounding Microenvironment

The inhibitory cosignaling pathway formed between the TNF receptor herpesvirus entry mediator (HVEM, TNFRSF14) and the Ig superfamily members, B and T lymphocyte attenuator (BTLA) and CD160, limits the activation of T cells. However, BTLA and CD160 can also serve as activating ligands for HVEM when...

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Autors principals: Cheung, Timothy C., Oborne, Lisa M., Steinberg, Marcos W., Macauley, Matthew G., Fukuyama, Satoshi, Sanjo, Hideki, D’Souza, Claire, Norris, Paula S., Pfeffer, Klaus, Murphy, Kenneth M., Kronenberg, Mitchell, Spear, Patricia G., Ware, Carl F.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865256/
https://ncbi.nlm.nih.gov/pubmed/19915044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902490
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