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Unconventional ligand activation of herpesvirus entry mediator signals cell survival
The herpesvirus entry mediator (HVEM; TNFRSF14) activates NF-κB through the canonical TNF-related cytokine LIGHT, serving as a costimulatory pathway during activation of T cells. HVEM also functions as a ligand for the Ig superfamily members B and T lymphocyte attenuator (BTLA) and CD160, both of wh...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669392/ https://ncbi.nlm.nih.gov/pubmed/19332782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902115106 |
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