Загрузка...
Antibody-mediated disruption of the interaction between PCSK9 and the low-density lipoprotein receptor
PCSK9 (proprotein convertase subtilisin/kexin type 9) promotes degradation of the LDLR [LDL (low-density lipoprotein) receptor] through an as-yet-undefined mechanism, leading to a reduction in cellular LDLc (LDL-cholesterol) and a concomitant increase in serum LDLc. Central to the function of PCSK9...
Сохранить в:
| Главные авторы: | , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Portland Press Ltd.
2009
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669217/ https://ncbi.nlm.nih.gov/pubmed/19196236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20082407 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|