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Multifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms
BACKGROUND: The fidelity of DNA replication serves as the nidus for both genetic evolution and genomic instability fostering disease. Single nucleotide polymorphisms (SNPs) constitute greater than 80% of the genetic variation between individuals. A new theory regarding DNA replication fidelity has e...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669078/ https://ncbi.nlm.nih.gov/pubmed/19331672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0381-2-2 |
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