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Genetic correlates of autoreactivity and autoreactive potential in human Ig heavy chains
BACKGROUND: Immature bone marrow B cells are known to have longer CDR3 than mature peripheral B cells, and this genetic characteristic has been shown to correlate with autoreactivity in these early cells. B-cell Central tolerance eliminates these cells, but it is known that autoreactive B cells neve...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669064/ https://ncbi.nlm.nih.gov/pubmed/19250530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-5-1 |
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