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Direct and Stereospecific Synthesis of Allenes via Reduction of Propargylic Alcohols with Cp(2)Zr(H)Cl

[Image: see text] Allenes can be synthesized via the direct S(N)2′ addition of hydride to propargylic alcohols. Previous examples of this approach, however, have involved harsh reaction conditions and have suffered from incomplete transfer of central chirality to axial chirality. Here we show that C...

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Autors principals: Pu, Xiaotao, Ready, Joseph M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668978/
https://ncbi.nlm.nih.gov/pubmed/18652467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8035527
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