Significant Associations of Mismatch Repair Gene Polymorphisms With Clinical Outcome of Pancreatic Cancer

PURPOSE: DNA mismatch repair (MMR) is critical in maintaining genomic stability and may modulate the cellular response to gemcitabine. We hypothesized that genetic variations in MMR may affect the clinical outcome of patients with pancreatic cancer. PATIENTS AND METHODS: We evaluated 15 single-nucle...

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Bibliografiske detaljer
Main Authors: Dong, Xiaoqun, Jiao, Li, Li, Yanan, Evans, Douglas B., Wang, Huamin, Hess, Kenneth R., Abbruzzese, James L., Li, Donghui
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2009
Fag:
Original Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668967/
https://ncbi.nlm.nih.gov/pubmed/19237629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.20.1111
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