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DNA Mismatch Repair Gene Polymorphisms Affect Survival in Pancreatic Cancer

PURPOSE. DNA mismatch repair (MMR) maintains genomic stability and mediates cellular response to DNA damage. We aim to demonstrate whether MMR genetic variants affect overall survival (OS) in pancreatic cancer. MATERIALS AND METHODS. Using the Sequenom method in genomic DNA, we retrospectively genot...

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Detalhes bibliográficos
Main Authors: Dong, Xiaoqun, Li, Yanan, Hess, Kenneth R., Abbruzzese, James L., Li, Donghui
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228057/
https://ncbi.nlm.nih.gov/pubmed/21212431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2010-0127
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