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Significant Impact of Homologous Recombination DNA Repair Gene Polymorphisms on Pancreatic Cancer Survival

Genetic variation in DNA repair may affect the clinical response to cytotoxic therapies. We investigated the effect of 6 SNPs of the RecQ1, RAD54L, XRCC2, and XRCC3 genes on overall survival of 378 patients with pancreatic adenocarcinoma who were treated at UT M.D. Anderson Caner Center during Febru...

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Main Authors: Li, Donghui, Liu, Hui, Jiao, Li, Chang, David Z., Beinart, Garth, Wolff, Robert A., Evans, Douglas B., Hassan, Manal M., Abbruzzese., James L.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462866/
https://ncbi.nlm.nih.gov/pubmed/16540687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-3032
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