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Accurate Prediction of Secreted Substrates and Identification of a Conserved Putative Secretion Signal for Type III Secretion Systems

The type III secretion system is an essential component for virulence in many Gram-negative bacteria. Though components of the secretion system apparatus are conserved, its substrates—effector proteins—are not. We have used a novel computational approach to confidently identify new secreted effector...

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Main Authors: Samudrala, Ram, Heffron, Fred, McDermott, Jason E.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668754/
https://ncbi.nlm.nih.gov/pubmed/19390620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000375
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