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A multi-pronged search for a common structural motif in the secretion signal of Salmonella enterica serovar Typhimurium type III effector proteins

Many pathogenic Gram-negative bacteria use a type III secretion system (T3SS) to deliver effector proteins into the host cell where they reprogram host defenses and facilitate pathogenesis. The first 20–30 N-terminal residues usually contain the ‘secretion signal’ that targets effector proteins for...

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Detalhes bibliográficos
Main Authors: Buchko, Garry W., Niemann, George, Baker, Erin S., Belov, Mikhail E., Smith, Richard D., Heffron, Fred, Adkins, Joshua N., McDermott, Jason E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282560/
https://ncbi.nlm.nih.gov/pubmed/20877914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mb00097c
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