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Accurate prediction of secreted substrates and identification of a conserved putative secretion signal for type III secretion systems.

The type III secretion system is an essential component for virulence in many Gram-negative bacteria. Though components of the secretion system apparatus are conserved, its substrates--effector proteins--are not. We have used a novel computational approach to confidently identify new secreted effect...

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Detalhes bibliográficos
Main Authors: Ram Samudrala, Fred Heffron, Jason E McDermott
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2009-04-01
Colecção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC2668754?pdf=render
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