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Aurora Kinase A Inhibition and Paclitaxel as Targeted Combination Therapy for Head and Neck Squamous Cell Carcinoma

BACKGROUND: Aurora kinase A (AURKA) is amplified with varying incidence in multiple human cancers including head and neck squamous cell carcinoma (HNSCC). We investigated whether AURKA is a potential therapeutic target in HNSCC. METHODS: We conducted an immunohistochemical analysis of AURKA expressi...

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Detalhes bibliográficos
Main Authors: Mazumdar, Abhijit, Henderson, Ying C., El-Naggar, Adel K., Sen, Subrata, Clayman, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668723/
https://ncbi.nlm.nih.gov/pubmed/19107951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.21007
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