Global mapping of protein-DNA interactions in vivo by digital genomic footprinting

The orchestrated binding of transcriptional activators and repressors to specific DNA sequences in the context of chromatin defines the regulatory program of eukaryotic genomes. We developed a digital approach to assay regulatory protein occupancy on genomic DNA in vivo by dense mapping of individua...

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Detalhes bibliográficos
Main Authors: Hesselberth, Jay R., Chen, Xiaoyu, Zhang, Zhihong, Sabo, Peter J., Sandstrom, Richard, Reynolds, Alex P., Thurman, Robert E., Neph, Shane, Kuehn, Michael S., Noble, William S., Fields, Stanley, Stamatoyannopoulos, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668528/
https://ncbi.nlm.nih.gov/pubmed/19305407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1313
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