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Global mapping of protein-DNA interactions in vivo by digital genomic footprinting
The orchestrated binding of transcriptional activators and repressors to specific DNA sequences in the context of chromatin defines the regulatory program of eukaryotic genomes. We developed a digital approach to assay regulatory protein occupancy on genomic DNA in vivo by dense mapping of individua...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668528/ https://ncbi.nlm.nih.gov/pubmed/19305407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1313 |
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