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Common Mitochondrial DNA Mutations generated through DNA-mediated Charge Transport
Mutation sites that arise in human mitochondrial DNA as a result of oxidation by a rhodium photooxidant have been identified. HeLa cells were incubated with [Rh(phi)(2)bpy]Cl(3) (phi = 9,10-phenanthrenequinone diimine), an intercalating photooxidant, to allow the complex to enter the cell and bind m...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668510/ https://ncbi.nlm.nih.gov/pubmed/19128037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801570j |
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