Loading...

Common Mitochondrial DNA Mutations generated through DNA-mediated Charge Transport

Mutation sites that arise in human mitochondrial DNA as a result of oxidation by a rhodium photooxidant have been identified. HeLa cells were incubated with [Rh(phi)(2)bpy]Cl(3) (phi = 9,10-phenanthrenequinone diimine), an intercalating photooxidant, to allow the complex to enter the cell and bind m...

Full description

Saved in:
Bibliographic Details
Main Authors: Merino, Edward J., Davis, Molly L., Barton, Jacqueline K.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668510/
https://ncbi.nlm.nih.gov/pubmed/19128037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801570j
Tags: Add Tag
No Tags, Be the first to tag this record!