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A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance
Charge transport (CT) through the DNA base pairs provides a means to promote redox reactions at a remote site and potentially to effect signaling between molecules bound to DNA. Here we describe the oxidation of a cell-cycle regulatory protein, p53, from a distance through DNA-mediated CT. A consens...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2141881/ https://ncbi.nlm.nih.gov/pubmed/18025460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709326104 |
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