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Replicon Particles of Venezuelan Equine Encephalitis Virus as a Reductionist Murine Model for Encephalitis

Venezuelan equine encephalitis virus (VEE) replicon particles (VRP) were used to model the initial phase of VEE-induced encephalitis in the mouse brain. VRP can target and infect cells as VEE, but VRP do not propagate beyond the first infected cell due to the absence of the structural genes. Direct...

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Hlavní autoři: Schäfer, Alexandra, Whitmore, Alan C., Konopka, Jennifer L., Johnston, Robert E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668494/
https://ncbi.nlm.nih.gov/pubmed/19225006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02383-08
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