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Replicon Particles of Venezuelan Equine Encephalitis Virus as a Reductionist Murine Model for Encephalitis

Venezuelan equine encephalitis virus (VEE) replicon particles (VRP) were used to model the initial phase of VEE-induced encephalitis in the mouse brain. VRP can target and infect cells as VEE, but VRP do not propagate beyond the first infected cell due to the absence of the structural genes. Direct...

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Detalhes bibliográficos
Main Authors: Schäfer, Alexandra, Whitmore, Alan C., Konopka, Jennifer L., Johnston, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668494/
https://ncbi.nlm.nih.gov/pubmed/19225006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02383-08
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