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Replicon Particles of Venezuelan Equine Encephalitis Virus as a Reductionist Murine Model for Encephalitis

Venezuelan equine encephalitis virus (VEE) replicon particles (VRP) were used to model the initial phase of VEE-induced encephalitis in the mouse brain. VRP can target and infect cells as VEE, but VRP do not propagate beyond the first infected cell due to the absence of the structural genes. Direct...

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מידע ביבליוגרפי
Main Authors: Schäfer, Alexandra, Whitmore, Alan C., Konopka, Jennifer L., Johnston, Robert E.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668494/
https://ncbi.nlm.nih.gov/pubmed/19225006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02383-08
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