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Acute Infection with Venezuelan Equine Encephalitis Virus Replicon Particles Catalyzes a Systemic Antiviral State and Protects from Lethal Virus Challenge

The host innate immune response provides a critical first line of defense against invading pathogens, inducing an antiviral state to impede the spread of infection. While numerous studies have documented antiviral responses within actively infected tissues, few have described the earliest innate res...

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Detalhes bibliográficos
Main Authors: Konopka, Jennifer L., Thompson, Joseph M., Whitmore, Alan C., Webb, Drue L., Johnston, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786707/
https://ncbi.nlm.nih.gov/pubmed/19793821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00564-09
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