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Acute Infection with Venezuelan Equine Encephalitis Virus Replicon Particles Catalyzes a Systemic Antiviral State and Protects from Lethal Virus Challenge

The host innate immune response provides a critical first line of defense against invading pathogens, inducing an antiviral state to impede the spread of infection. While numerous studies have documented antiviral responses within actively infected tissues, few have described the earliest innate res...

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Autors principals: Konopka, Jennifer L., Thompson, Joseph M., Whitmore, Alan C., Webb, Drue L., Johnston, Robert E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786707/
https://ncbi.nlm.nih.gov/pubmed/19793821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00564-09
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