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Identification of a Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Variant Resistant to Cold Inactivation

The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein trimer consists of gp120 and gp41 subunits and undergoes a series of conformational changes upon binding to the receptors, CD4 and CCR5/CXCR4, that promote virus entry. Surprisingly, we found that the envelope glycoproteins of som...

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Detalhes bibliográficos
Main Authors: Kassa, Aemro, Finzi, Andrés, Pancera, Marie, Courter, Joel R., Smith, Amos B., Sodroski, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668461/
https://ncbi.nlm.nih.gov/pubmed/19211747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02110-08
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