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Proteasomal Degradation of the Papillomavirus E2 Protein Is Inhibited by Overexpression of Bromodomain-Containing Protein 4

The E2 protein of human papillomavirus (HPV) binds to specific sites in the viral genome to regulate its transcription, replication, and maintenance in infected cells. Like most regulatory proteins, E2 is rapidly turned over. A high-throughput assay was developed to quantify the expression and stabi...

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Main Authors: Gagnon, David, Joubert, Simon, Sénéchal, Hélène, Fradet-Turcotte, Amélie, Torre, Sabrina, Archambault, Jacques
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668459/
https://ncbi.nlm.nih.gov/pubmed/19211738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02468-08
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