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Heterologous Expression of Mycobacterial Proteins in Saccharomyces cerevisiae Reveals Two Physiologically Functional 3-Hydroxyacyl-Thioester Dehydratases, HtdX and HtdY, in Addition to HadABC and HtdZ

We report on Mycobacterium tuberculosis Rv0241c and Rv3389c, representing two physiologically functional 3-hydroxyacyl-thioester dehydratases (Htd). These enzymes are potentially entrained in type 2 fatty acid synthase (FASII). Mycobacterial FASII is involved in the synthesis of mycolic acids, which...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gurvitz, Aner, Hiltunen, J. Kalervo, Kastaniotis, Alexander J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668405/
https://ncbi.nlm.nih.gov/pubmed/19136596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01046-08
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