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Enhanced Antibody Responses Elicited by a CpG Adjuvant Do Not Improve the Protective Effect of an Aldrithiol-2-Inactivated Simian Immunodeficiency Virus Therapeutic AIDS Vaccine

The potential benefit of using unmethylated CpG oligoribodeoxynucleotides (ODN) as an adjuvant in a therapeutic simian immunodeficiency virus (SIV) vaccine consisting of AT2-inactivated SIVmac239 was evaluated in SIV-infected rhesus macaques receiving antiretroviral therapy (ART). We hypothesized th...

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Detalhes bibliográficos
Principais autores: Wang, Yichuan, Blozis, Shelley A., Lederman, Michael, Krieg, Arthur, Landay, Alan, Miller, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668268/
https://ncbi.nlm.nih.gov/pubmed/19225080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00471-08
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